NanoBiotechnology with DNA ‘Bricks’

Versatile 3D Nanostructures Using DNA “Bricks”

Researchers from the “Wyss Institute for Biologically Inspired Engineering” (Harvard University) have reported a revolutionnary method that greatly expands the repertoire of nanobiotechnology applications in medicine & beyond. The nanofabrication technique, called “DNA-brick self-assembly,” uses short, synthetic strands of DNA that work like interlocking Lego® bricks. It capitalizes on the ability to program DNA to form into predesigned shapes thanks to the underlying “recipe” of DNA base pairs: A (adenosine) only binds to T (thymine) and C (cytosine) only binds to G (guanine). To understand more about this incredible molecular “LEGO®” assembly process, watch the following two videos issued by the researchers. Really mind-boggling !!!.

“Researchers at the Wyss Institute for Biologically Inspired Engineering at Harvard University have created more than 100 three-dimensional (3D) nanostructures using DNA building blocks that function like Lego® bricks — a major advance from the two-dimensional (2D) structures the same team built a few months ago” from Science Daily.

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